Mode Peptides KPV 10 MG is a premium-grade anti-inflammatory tripeptide supplied as a stable, lyophilized powder for advanced laboratory research.

KPV (Lysine-Proline-Valine) is a naturally occurring C-terminal tripeptide fragment derived from the alpha-Melanocyte Stimulating Hormone (α-MSH). Unlike the full-length α-MSH, KPV is specifically studied for its potent, localized anti-inflammatory properties without the significant melanotropic effects. It acts as a highly effective antagonist of inflammatory signaling cascades, making it a central focus in research on inflammatory bowel disease, wound healing, and dermatological inflammation. Its small molecular size allows for excellent cellular penetration and stability in various experimental models.

The lyophilized powder format ensures maximum peptide integrity, extended shelf-life, and precise reconstitution, allowing researchers to achieve accurate and reproducible dosing for both in-vitro cell culture assays and in vivo preclinical studies.

Product Specifications of KPV 10 mg:

• Product Name: KPV 10 MG
• Dosage: 10 MG per vial
• Form: Lyophilized Powder
• Purity: >99%
• Molecular Formula: C20H37N6O5
• Molecular Weight: 442.55 g/mol
• Amino Acid Sequence: Lys-Pro-Val (KPV)
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in water, bacteriostatic water, and PBS

Research Applications:

Researchers extensively use KPV 10 MG in research models investigating NF-κB inflammatory pathway inhibition, inflammatory bowel disease (IBD), including ulcerative colitis models, intestinal mucosal inflammation and barrier function, wound healing and fibroblast proliferation, skin inflammation, atopic dermatitis and psoriasis models, pro-inflammatory cytokine reduction (TNF-α, IL-1β, IL-6), antimicrobial peptide properties, and intracellular anti-inflammatory mechanisms. Because KPV can enter cells and act intracellularly, researchers study its ability to enter inflammatory cells, influence cytokine release at the cellular level, and support tissue homeostasis without systemic immunosuppression. Researchers also investigate KPV in dermal and mucosal healing models to evaluate wound closure and scar formation, making it relevant to gastroenterology, immunology, and dermatology research.

Quality & Storage of KPV 10 mg:

Every batch is accompanied by a Certificate of Analysis (COA). For proper storage, keep the unreconstituted vial at -20°C in a dry, dark place and protect it from moisture. When reconstituting, use sterile bacteriostatic water under appropriate aseptic laboratory conditions. After reconstitution, store the material at 2–8°C and follow established laboratory protocols for handling and use. Additionally, avoid repeated freeze-thaw cycles to help maintain sample integrity. Finally, this material is for research use only.

Research Use Only